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肝原位模型通過將肝癌組織塊直接在小鼠肝臟進行移植，建立肝癌原位模型，相對皮下成瘤模型，更加模擬肝癌的實際生長情況。
先制備皮下成瘤模型，取出皮下腫瘤，切成小塊；通過外科手術，將腫瘤塊接種到動物肝臟上，制備肝原位移植模型，通過借助小動物活體成像儀器觀察動物肝臟上腫瘤的形成、增殖以及體內轉移灶的發生、發展情況，評價細胞的肝原位成瘤能力以及在動物體內的轉移能力，主要適用于肝癌在體內原位成瘤和轉移方向的研究?？商峁┑慕＜毎涤校焊伟┑?。
肝癌細胞感染攜帶有Luc的慢病毒，原位接種于4周齡裸小鼠肝臟，4周后，活體成像?？梢娐闶篌w內有腫瘤形成。
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